Amakin Artemether & Lumefantrine 80 mg/480 mg Tablets

Amakin Artemether & Lumefantrine Tablets (80 mg/480 mg) are oral, fixed-dose combination antimalarial tablets designed for the effective treatment of uncomplicated malaria. This formulation contains Artemether and Lumefantrine, two complementary agents recommended globally as first-line therapy for Plasmodium falciparum malaria. The tablets are manufactured by Kesar Pharma Pvt Ltd. in India.

Product Details

Active Ingredients (per tablet)

• Artemether: 80 mg
• A fast-acting artemisinin derivative that promptly reduces malaria parasite levels in the bloodstream.
• Lumefantrine: 480 mg
• A longer-acting antimalarial that works synergistically with artemether to clear residual parasites and prevent recurrence.

Excipients

• Excipients q.s. (quantum satis)
• Colour: Tartrazine Yellow

Dosage Form and Description

• Form: Film-coated tablet
• Appearance: Round, lake tartrazine yellow tablet with a score line and "80/480" engraved on the surface, allowing for accurate splitting and identification.

Route of Administration

• Oral: To be taken by mouth, preferably with food or a milk-based drink to enhance lumefantrine absorption.

Indications and Usage

Amakin Artemether & Lumefantrine 80 mg/480 mg Tablets are indicated for:

• Treatment of uncomplicated malaria caused by Plasmodium falciparum, including strains resistant to older antimalarial medications.

This dosage is especially suited for adults and older children, in accordance with national and international malaria treatment guidelines.

Dosage and Administration

• Recommended Dosage:
• The dosage regimen is determined by body weight and age, as prescribed by a healthcare provider. The usual course consists of six doses over three days. Completing the full treatment regimen is essential for optimal efficacy and to prevent resistance.
• Administration Advice:
• Take the tablet with food to maximize absorption. The score line allows for dose adjustment if necessary.

Packaging

• Pack Size: 1 x 6’s (six tablets per Alu/PVC blister), providing a complete treatment course for most adult and adolescent patients.

Safety Information

• Contraindications:
• Not for use in individuals with known hypersensitivity to artemether, lumefantrine, or any tablet component.
• Precautions:
• Use with caution in patients with severe malaria, cardiac rhythm disorders, or those taking medications that may prolong the QT interval. Consult a healthcare provider before use during pregnancy or breastfeeding.
• Possible Side Effects:
• Common: headache, dizziness, appetite loss, abdominal discomfort, mild gastrointestinal symptoms.
• Rare: allergic reactions or cardiac rhythm disturbances.
• Drug Interactions:
• Inform your healthcare provider about all medications being taken, especially other antimalarial drugs, antibiotics, or medicines that affect heart rhythm.

Storage Conditions

• Store in a cool, dry place below 30°C.
• Protect from moisture and light.
• Keep out of reach of children.

Note

This article provides general product information and does not replace professional medical advice. Always consult your healthcare provider for correct diagnosis, dosing, and completion of antimalarial therapy.