[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"product-dactinomycin-inj-5mg":3},{"product":4,"offer":18,"noindex":24,"canonical":53},{"id":5,"name":6,"slug":7,"brand":8,"description":9,"picture_path":10,"thumbnail_path":10,"category_id":11,"dossage":12,"direction_of_use":13,"nafdac":14,"is_genuine":15,"is_new":16,"require_prescription":15,"created_at":17,"updated_at":17},5845,"DACTINOMYCIN INJ 5mg","dactinomycin-inj-5mg","Drugstore","\u003Cp>\u003Cspan>Dactinomycin (also known as Actinomycin D) is a heavy-hitting medication used in the fight against several specific types of cancer. Because it is a potent \"cytotoxic antibiotic,\" it is handled with extreme care by medical teams. \u003C\u002Fspan>\u003C\u002Fp>\u003Ch3>\u003Cspan>What is Dactinomycin Used For?\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>Unlike common antibiotics used for infections, Dactinomycin is an antineoplastic antibiotic—it is used exclusively as chemotherapy to stop cancer cells from multiplying. It is primarily used to treat:\u003C\u002Fspan>\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cspan>Wilms’ Tumor: A type of kidney cancer that usually occurs in children.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Rhabdomyosarcoma: A rare cancer of the soft tissues (like muscle).\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Ewing’s Sarcoma: Cancer that grows in the bones or the soft tissue around them.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Gestational Trophoblastic Neoplasia: A rare tumor that forms in the uterus during pregnancy.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Testicular Cancer: Specifically, certain advanced types that haven't responded to other treatments.\u003C\u002Fspan>\u003C\u002Fli>\u003C\u002Ful>\u003Ch3>\u003Cspan>Ingredients\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>Dactinomycin is typically supplied as a lyophilized (freeze-dried) powder in a vial that must be reconstituted by a professional before use.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>Active Ingredient: Dactinomycin (0.5 mg or 500 mcg per vial).\u003C\u002Fspan>\u003C\u002Fp>\u003Ch3>\u003Cspan>How It Works (Mechanism of Action)\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>Cancer cells grow and divide much faster than normal cells. Dactinomycin stops this process by targeting the cell's \"instruction manual,\" the DNA.\u003C\u002Fspan>\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cspan>Intercalation: The drug molecules slide themselves between the \"rungs\" of the DNA ladder (specifically at guanine-cytosine base pairs).\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Transcription Block: By sitting inside the DNA, it blocks an enzyme called RNA polymerase. Think of it like putting a wedge in a zipper; the enzyme can't move down the DNA strand to create RNA.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Protein Shutdown: Without RNA, the cell cannot make the proteins it needs to survive or divide.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Cell Death: The cancer cell eventually stops growing and dies (apoptosis).\u003C\u002Fspan>\u003C\u002Fli>\u003C\u002Ful>\u003Ch3>\u003Cspan>Dosage and Administration\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>Dactinomycin is a vesicant, meaning it is extremely corrosive. If it leaks out of the vein into the surrounding skin (extravasation), it can cause severe tissue death. It must only be given by a specialist.\u003C\u002Fspan>\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cspan>Standard Adult Dose: Often ranges from 10–15 mcg\u002Fkg daily for 5 days, or a single larger dose of up to 2.5 mg every 3 weeks, depending on the specific cancer protocol.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Pediatric Dose: Similar weight-based calculations are used (e.g., 45 mcg\u002Fkg for Wilms' Tumor), but infants under 6–12 months require extra caution due to toxicity risks.\u003C\u002Fspan>\u003C\u002Fli>\u003C\u002Ful>\u003Ch3>\u003Cspan>Dactinomycin Side Effects\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>Because Dactinomycin attacks rapidly dividing cells, it can also affect healthy cells in the hair, gut, and blood.\u003C\u002Fspan>\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cspan>Bone Marrow Suppression: This is the most serious side effect. It lowers your white blood cells (increasing infection risk), red blood cells (causing fatigue), and platelets (causing easy bruising).\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Gastrointestinal Issues: Severe nausea and vomiting (often starting shortly after injection), mouth sores, and diarrhea.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Radiation Recall: If a patient has had radiation therapy in the past, Dactinomycin can cause the skin in that specific area to become red, blistered, or painful again.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Liver Toxicity: In some cases, especially in children, it can cause liver swelling or \"Veno-Occlusive Disease\" (VOD).\u003C\u002Fspan>\u003C\u002Fli>\u003C\u002Ful>\u003Ch3>\u003Cspan>Frequently Asked Questions (FAQs)\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>1. Why is it called an \"antibiotic\" if it treats cancer?\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>It was originally discovered from a bacterium (Streptomyces parvulus). While it can kill bacteria, it is far too toxic to be used for simple infections, so its power is reserved for killing cancer cells.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>2. Does it cause hair loss?\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>Yes, thinning or complete hair loss (alopecia) is a common side effect. Fortunately, the hair almost always grows back once the treatment cycles are finished.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>3. Why do health care workers wear extra protective gear when giving this?\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cspan>Because Dactinomycin is \"genotoxic\" (it can damage DNA), healthcare workers must prevent even tiny amounts from touching their skin or being inhaled.\u003C\u002Fspan>\u003C\u002Fp>\u003Ch3>\u003Cspan>Conclusion\u003C\u002Fspan>\u003C\u002Fh3>\u003Cp>\u003Cspan>Dactinomycin is a potent, time-tested tool in oncology. While its side effects can be intense and its administration requires expert precision, it remains a \"gold standard\" for treating specific pediatric and reproductive cancers. By effectively \"jamming\" the machinery of cancer cells, it provides a pathway to remission for thousands of patients every year.\u003C\u002Fspan>\u003C\u002Fp>\u003Cp>\u003Cbr \u002F>\u003C\u002Fp>\u003Cp>\u003Cbr \u002F>\u003C\u002Fp>",null,31,"\u003Cp>\u003Cspan>Dactinomycin is a vesicant, meaning it is extremely corrosive. If it leaks out of the vein into the surrounding skin (extravasation), it can cause severe tissue death. It must only be given by a specialist.\u003C\u002Fspan>\u003C\u002Fp>\u003Cul>\u003Cli>\u003Cspan>Standard Adult Dose: Often ranges from 10–15 mcg\u002Fkg daily for 5 days, or a single larger dose of up to 2.5 mg every 3 weeks, depending on the specific cancer protocol.\u003C\u002Fspan>\u003C\u002Fli>\u003Cli>\u003Cspan>Pediatric Dose: Similar weight-based calculations are used (e.g., 45 mcg\u002Fkg for Wilms' Tumor), but infants under 6–12 months require extra caution due to toxicity risks.\u003C\u002Fspan>\u003C\u002Fli>\u003C\u002Ful>\u003Cp>\u003Cbr \u002F>\u003C\u002Fp>","null","false",0,1,"2026-06-25T22:21:49.000000Z",{"id":19,"is_new":16,"name":6,"quantity":20,"review_count":15,"price":21,"featured":24,"sold_count":15,"brand":8,"picture_path":10,"thumbnail_path":10,"whatsapp_url":25,"category":26,"company":33,"dossage":46,"direction_of_use":47,"slug":7,"nafdac":14,"is_genuine":15,"created_at":48,"updated_at":49,"description":50,"links":51,"require_prescription":24,"superbowl_featured":24},44870,10,{"digit":22,"text":23},"9350.00","₦9,350",false,"https:\u002F\u002Fwa.me\u002F2347019063866?text=Hello+Drugstore+Nigeria+Online+Pharmacy%2C+I+am+reaching+out+from+Drugstore.ng%0A%0AI+want+to+buy++%2A+DACTINOMYCIN+INJ+5mg%2A%2C+%2APrice%2A%3A+%E2%82%A69%2C350%2C+%2AURL%2A%3A+https%3A%2F%2Fdrugstore.ng%2F2%2Fstock%2Fdactinomycin-inj-5mg%0A%0AThank+you%21",{"id":27,"name":28,"parent":15,"description":29,"sub_categories":30,"links":31},14,"Anti-Cancer","Cancer treatment",[],{"drugs":32},"https:\u002F\u002Fapi.drugstore.com.ng\u002Fget\u002Fdrugs?category=Anti-Cancer",{"id":34,"plan":35,"plan_expires_at":10,"product_limit_override":36,"company_name":37,"street_address":38,"city":39,"state":40,"picture_path":10,"pcn_license_path":10,"pcn_license_source":10,"pcn_license_reference":10,"pcn_license_recorded_by":10,"pcn_license_recorded_at":10,"license_gate_from":10,"license_exempt":41,"country":42,"longitude":10,"latitude":10,"l_g_a_id":43,"device_id":10,"phone_number":10,"whatsapp_number":10,"weekly_report_emails":10,"chat_contact_name":10,"chat_contact_phone":10,"chat_contact_email":10,"created_at":44,"updated_at":45},2,"gold",1000000,"Drugstore Nigeria Online Pharmacy","NULL","Ikeja","Lagos",true,"Nigeria",494,"2018-03-05T03:20:02.000000Z","2026-07-25T21:10:31.000000Z","Dactinomycin is administered by a healthcare professional as an intravenous (IV) injection or infusion. The dose and frequency depend on the specific cancer, the patient's body size, and the treatment schedule. It is typically given in cycles as part of a combination of multiple chemotherapy drugs. Always follow your oncologist's instructions.","Before and during treatment, your doctor will perform regular blood tests to check blood cell counts and liver and kidney function. Dactinomycin can cause severe immunosuppression; avoid live vaccines during treatment. Inform your healthcare team immediately if you experience signs of infection, unusual bleeding, jaundice, abdominal swelling, or pain at the injection site. This medicine is for use only in a hospital or clinical setting under specialist care.","2022-05-31T17:20:24.000000Z","2026-07-19T20:24:51.000000Z","\u003Cp>Dactinomycin 5mg Injection is an actinomycin antibiotic used as part of combination chemotherapy for several types of cancer in adults and children. It is given by intravenous injection under strict medical supervision.\u003C\u002Fp>\u003Ch2>What it is\u003C\u002Fh2>\u003Cp>Dactinomycin is an actinomycin antibiotic. It belongs to a class of medicines called antineoplastic agents, which work by interfering with the growth of cancer cells.\u003C\u002Fp>\u003Ch2>What it's used for\u003C\u002Fh2>\u003Cp>Dactinomycin is used as part of multi-drug chemotherapy regimens for: Wilms tumor (a type of kidney cancer in children), rhabdomyosarcoma (cancer of muscle tissue), Ewing sarcoma (bone or soft tissue cancer), metastatic nonseminomatous testicular cancer, and gestational trophoblastic neoplasia (pregnancy-related tumors).\u003C\u002Fp>\u003Ch2>Common side effects\u003C\u002Fh2>\u003Cp>Serious side effects include myelosuppression (low red blood cells, white blood cells, and platelets), veno-occlusive disease (liver damage), severe mucocutaneous reactions, increased risk of secondary cancers, kidney toxicity, and liver toxicity. Extravasation (leakage from the vein) can cause tissue damage. Your doctor will monitor you closely.\u003C\u002Fp>\u003Ch2>Important cautions\u003C\u002Fh2>\u003Cp>Before and during treatment, your doctor will perform regular blood tests to check blood cell counts and liver and kidney function. Dactinomycin can cause severe immunosuppression; avoid live vaccines during treatment. Inform your healthcare team immediately if you experience signs of infection, unusual bleeding, jaundice, abdominal swelling, or pain at the injection site. This medicine is for use only in a hospital or clinical setting under specialist care.\u003C\u002Fp>\u003Ch2>Frequently asked questions\u003C\u002Fh2>\u003Ch3>What is Dactinomycin used for?\u003C\u002Fh3>\u003Cp>Dactinomycin is used in combination chemotherapy to treat Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, certain testicular cancers, and gestational trophoblastic neoplasia.\u003C\u002Fp>\u003Ch3>Is Dactinomycin a chemotherapy drug?\u003C\u002Fh3>\u003Cp>Yes, Dactinomycin is a chemotherapy medication used to treat several types of cancer.\u003C\u002Fp>\u003Ch3>Does Dactinomycin have side effects?\u003C\u002Fh3>\u003Cp>Yes, serious side effects include low blood counts, liver and kidney toxicity, and an increased risk of secondary cancers. Your doctor will monitor you for these.\u003C\u002Fp>\u003Ch3>How is Dactinomycin taken?\u003C\u002Fh3>\u003Cp>It is given by injection into a vein by a healthcare professional, typically in cycles as part of a combination chemotherapy regimen.\u003C\u002Fp>\u003Ch3>Can I buy Dactinomycin without a prescription in Nigeria?\u003C\u002Fh3>\u003Cp>According to the product information, Dactinomycin 5mg Injection is classified as over-the-counter in Nigeria. However, it is a potent chemotherapy medicine and must only be used under the close supervision of a qualified healthcare professional.\u003C\u002Fp>\u003Cp class=\"content-disclaimer\">\u003Cem>This information is for general guidance only and is not medical advice. Please consult your physician or pharmacist before using any medication.\u003C\u002Fem>\u003C\u002Fp>",{"info":52},"https:\u002F\u002Fapi.drugstore.com.ng\u002Fget\u002Fdrug\u002Finfo\u002F44870","\u002Fproduct\u002Fdactinomycin-inj-5mg"]