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Zoloft (sertraline) is a selective serotonin reuptake inhibitor (SSRI) used to treat major depressive disorder, obsessive-compulsive disorder, panic disorder, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder. What it is Zoloft contains sertraline, an SSRI antidepressant. It works by increasing serotonin levels in the brain to help improve
